2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide

204205-90-3

CAS番号.	204205-90-3
化学名:
别名:
英語化学名:	2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide
英語别名:	ZIO 301;Indibulin;Nascapine;lindiblin;2-[1-(4-Chlorobenzyl)-1H-indol-3-yl]-2-oxo-N-pyridin-4-ylacetamide;2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide
CBNumber:	CB12128730
分子式:	C22H16ClN3O2
分子量:	389.83
MOL File:	204205-90-3.mol

2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide 物理性質

貯蔵温度 :

Desiccate at -20°C

安全性情報

2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide 化学特性,用途語,生産方法

生物活性
Microtubule destabilizer that blocks tubulin polymerization (IC 50 = 0.3 μ M). Blocks cell cycle progression at metaphase and displays antitumor activity against a variety of malignancies in vitro (IC 50 values ranging from 0.036-0.285 μ M). Induces complete tumor remission in the Yoshida AH13 rat sarcoma model in vivo . Lacks neurotoxicity due to an ability to discriminate between posttranslationally modified tubulin in mature neuronal microtubules and less-modified tubulin present in immature neuronal or nonneuronal microtubules. Displays oral availability and efficacy towards MDR tumor cells.

2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide 上流と下流の製品情報

原材料

準備製品

2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide 生産企業 Global( 14)Suppliers

名前	電話番号	ファックス番号	電子メール	国籍	製品カタログ	優位度
3B Pharmachem (Wuhan) International Co.,Ltd.	86-21-50328103 * 801、802、803、804 Mobile:18930552037	86-21-50328109	67055399@qq.com	CHINA	15983	69
ZHIWE CHEMTECH CO LTD	021-20221225;13917446399；QQ:2381298399		sales@zhiwe.net;zwchem@163.com	CHINA	297	61
VDM Biochemicals	0330-2528181	0330-2528171	sales@vdmbio.com	USA	511	64
BOC Sciences	1-631-504-6093	1-631-614-7828	sales@bocsci.com	USA	9972	65
Shanghai Balmxy Pharmaceutical Co., Ltd	86-021-24206007	86-021-51862108	sales@balmxy.com	CHINA	507	55
AN PharmaTech Co Ltd	86(21)68097365	86(21)33321566	sales@anpharma.net	CHINA	4909	55
EMMX Biotechnology LLC	888-539-0666	888-539-0666	info@emmx.com	USA	8489	60

204205-90-3(2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide) キーワード:

4'-クロロアセトアニリド N,N-ジメチルアセトアミドジアセトアミドアセトアミド 4'-ヒドロキシアセトアニリドチオアセトアミド 2-クロロアセトアミド

204205-90-3 2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide Indibulin 2-[1-(4-Chlorobenzyl)-1H-indol-3-yl]-2-oxo-N-pyridin-4-ylacetamide lindiblin Nascapine ZIO 301