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| CAS番号. | 182498-32-4 |
| 化学名: | |
| 别名: | |
| 英語化学名: | SB 225002 |
| 英語别名: | SB 225002;N-(2-BROMOPHENYL)-N'-(2-HYDROXY-4-NITROPHENYL)UREA;N-(2-HYDROXY-4-NITROPHENYL)-N'-(2-BROMOPHENYL)UREA |
| CBNumber: | CB1455331 |
| 分子式: | C13H10BrN3O4 |
| 分子量: | 352.14 |
| MOL File: | 182498-32-4.mol |
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SB 225002 化学特性,用途語,生産方法 |
生物活性
Potent and selective CXCR2 chemokine receptor antagonist (IC 50 = 22 nM) that displays > 150-fold selectivity over CXCR1 receptors. Causes inhibition of IL-8 and GRO α -mediated calcium mobilization in HL60 cells (IC 50 values are 8 and 10 nM respectively). Prevents IL-8-induced neutrophil chemotaxis in vitro and sequestration in vivo . Inhibits HIV replication in lymphocytes and macrophages. |
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| SB 225002 上流と下流の製品情報 |
原材料
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準備製品
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| SB 225002 生産企業 Global( 18)Suppliers |
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