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CAS番号. | 141196-69-2 |
化学名: | |
别名: | |
英語化学名: | 7-oxostaurosporine |
英語别名: | 7-oxostaurosporine;Oxostaurosporine, 7-;7-Oxostaurosporine, BMY 41950, RK 1409 |
CBNumber: | CB81342231 |
分子式: | C28H24N4O4 |
分子量: | 480.522 |
MOL File: | 141196-69-2.mol |
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7-oxostaurosporine 化学特性,用途語,生産方法 |
使用
7-Oxostaurosporine is the oxidised and highly fluorescent analogue of UCN-01 and UCN-02. 7-Oxostaurosporine is a potent inhibitor of protein kinase C and formation of cellular blebs induced by phorbols. It inhibits the cell cycle at the G2 stage with the accumulation of 4C DNA cells and possesses comparable activity against tumour cells lines to UCN-01. Despite its close relationship to UCN-01 and staurosporine, limited access to the metabolite has restricted a more complete investigation of its properties. |
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使用
7-Oxostaurosporine is the oxidised and highly fluorescent analogue of UCN-01 and UCN-02. 7-Oxostaurosporine is a potent inhibitor of protein kinase C and formation of cellular blebs induced by phorbols. It inhibits the cell cycle at the G2 stage with the accumulation of 4C DNA cells and possesses comparable activity against tumor cells lines to UCN-01. Despite its close relationship to UCN-01 and staurosporine, limited access to the metabolite has restricted a more complete investigation of its properties. |
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7-oxostaurosporine 上流と下流の製品情報 |
原材料
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準備製品
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7-oxostaurosporine 生産企業 Global( 2)Suppliers |
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