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| CAS番号. | 154639-24-4 |
| 化学名: | |
| 别名: | |
| 英語化学名: | RK-682 |
| 英語别名: | RK-682;TAN 1364B;ANTIBIOTIC RK-682;ANTIBIOTIC TAN 1364B;RK-682, STREPTOMYCES SPECIES;3-HEXADECANOYL-5-HYDROXYMETHYL-TETRONIC ACID;CI 010, 3-hexadecanoyl-5-hydroxyMethyltetronic acid. |
| CBNumber: | CB9706972 |
| 分子式: | C21H36O5 |
| 分子量: | 368.51 |
| MOL File: | 154639-24-4.mol |
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RK-682 化学特性,用途語,生産方法 |
使用
TAN 1364B (RK-682) is the most abundant analogue of a tetronic acid complex isolated from Streptomyces species, first patented by Takeda in 1993 and more formally identified by Ciba Geigy as the sodium salt of 3-hexadecanoyl-5-hydroxymethyltetronic acid. In 1995 researchers at RIKEN reported the isolation of 3-hexadecanoyl-5-hydroxymethyltetronic acid, named as RK-682. Subsequent synthesis in 2001 showed that the RIKEN RK-682 was in fact the calcium complex of TAN 1364B formed as an artefact during silica chromatography. As the complex, salt or free acid, TAN 1364B inhibits protein tyrosine phosphatases, phospoholipase A2, heparinase and HIV-1 protease. However, it is unclear whether biological activity is due to the monomer (TAN 1364B) or dimeric complex (RK-682) |
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使用
TAN 1364B is the most abundant analogue of a tetronic acid complex isolated from Streptomyces species, first patented by Takeda in 1993 and more formally identified by Ciba Geigy as the sodium salt of 3-hexadecanoyl-5-hydroxymethyltetronic acid. In 1995 researchers at RIKEN reported the isolation of 3-hexadecanoyl-5-hydroxymethyltetronic acid, named as RK-682. Subsequent synthesis in 2001 showed that the RIKEN RK-682 was in fact the calcium complex of TAN 1364B formed as an artefact during silica chromatography. As the complex, salt or free acid, TAN 1364B inhibits protein tyrosine phosphatases, phospoholipase A2, heparinase and HIV-1 protease. However, it is unclear whether biological activity is due to the monomer (TAN 1364B) or dimeric complex (RK-682) |
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| RK-682 上流と下流の製品情報 |
原材料
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準備製品
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| RK-682 生産企業 Global( 6)Suppliers |
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