(1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone Suppliers list |
Company Name: | BOC Sciences Gold |
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Product Name:RoMidepsin; Istodax CAS:128517-07-7
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Company Name: | Shanghai Boyle Chemical Co., Ltd. |
Tel: | Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market) |
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Product Name:FK228 CAS:128517-07-7 Purity:98%min Package:100G,1KG.5KG |
Company Name: | J & K SCIENTIFIC LTD. |
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Product Name:RoMidepsin CAS:128517-07-7 Package:1Mg,5Mg |
Company Name: | Chembest Research Laboratories Limited |
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Product Name:RoMidepsin/Depsipeptide(FK-228, NSC-63017) CAS:128517-07-7 Remarks:C14119 |
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| (1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone Basic information |
Product Name: | (1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone | Synonyms: | (1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone;FR 901228;Romidepsin;istodax;RoMidepsin/Depsipeptide(FK-228, NSC-63017);[S-(E)]-N-(3-Hydroxy-7-Mercapto-1-oxo-4-
heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aMinobutanoyl-;Cyclo[(2Z)-2-aMino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-Mercapto-4-heptenoyl-D-valyl-D-cysteinyl] Cyclic (35)-Disulfide;Cyclo[(2Z)-2-aMino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-Mercapto-4-heptenoyl-D-valyl-D-cysteinyl]-d8 Cyclic (35)-Disulfide | CAS: | 128517-07-7 | MF: | C24H36N4O6S2 | MW: | 0 | EINECS: | | Product Categories: | Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitor;API | Mol File: | 128517-07-7.mol | |
| (1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone Chemical Properties |
mp | 219-224°C | density | 1.174 | storage temp. | Amber Vial, -20°C Freezer, Under Inert Atmosphere |
| (1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone Usage And Synthesis |
Chemical Properties | Pale Yellow Solid | Usage | Labelled Romidepsin (R425060). Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This
may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xeno
graft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor. |
| (1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone Preparation Products And Raw materials |
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