| Company Name: | Dalian Meilun Biotech Co., Ltd. Gold |
| Tel: | 0411-66771943；0411-66771942 |
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| Products Intro: |
Product Name:MitoMycin C
CAS:50-07-7
Package:10Mg,50Mg,100Mg,1g. |
| Company Name: | MedChemexpress LLC Gold |
| Tel: | 609-228-6898 |
| Email: | sales@medchemexpress.cn |
| Products Intro: |
Product Name:Mitomycin C
CAS:50-07-7
Purity:>98% Package:50mg;5mg; |
| Company Name: | Shanghai Hanjing Chemicals Co., Ltd. Gold |
| Tel: | +86 (21) 3700-9251 / 3700-9252 |
| Email: | sales@hanjinggroup.com, zongjf@sina.com |
| Products Intro: |
Product Name:Mitomycin C
CAS:50-07-7
Purity:USP,NON-STERILE Package:1GRAM;10GRAM,100GRAM |
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| | Mitomycin C Basic information |
| Product Name: | Mitomycin C | | Synonyms: | )methyl)-1,1a,2,8,8a,8b-hexahydro-8-a-methoxy-5-methyl-,(1as-(1aalpha,8beta,;7-amino-9-alpha-methoxymitosane;8aalpha,8balpha))-(9ci);8balpha)]-8aalph;ametycine;azirino(2’,3’:3,4)pyrrolo(1,2-a)indole-4,7-dione,6-amino-1,1a,2,8,8a,8b-hexahy;azirino(2’,3’:3,4)pyrrolo(1,2-a)indole-4,7-dione,6-amino-8-(((aminocarbonyl)oxy;azirino[2’,3’:3,4]pyrrolo[1,2-a]indole-4,7-dione,6-amino-8-[[(aminocarbonyl)ox | | CAS: | 50-07-7 | | MF: | C15H18N4O5 | | MW: | 334.33 | | EINECS: | 200-008-6 | | Product Categories: | Antibiotics;Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;Antibiotics G-MAntibiotics;AntibioticsStem Cell Expansion;AziridinesStem Cell Biology;DissociationAntibiotics;Interferes with DNA SynthesisMore...Close...;Antibiotics A to;Antibiotics by Application;AntibioticsAntibiotics;Antineoplastic and Immunosuppressive AntibioticsAntibiotics;Cell Culture;Chemical Structure Class;Culture;Mechanism of Action;Reagents and Supplements;Stem Cell Isolation;AziridinesAntibiotics;Core Bioreagents;Interferes with DNA Synthesis;Research Essentials;Apoptosis Inducers;Amines;Chiral Reagents;Heterocycles;API;MUTAMYCIN;antibiotic;Anti-cancer&immunity | | Mol File: | 50-07-7.mol |  |
| | Mitomycin C Chemical Properties |
| mp | 360 °C | | storage temp. | 2-8°C
| | solubility | H2O: 4 mL/vial Stock solutions should be filter sterilized and stored at 2-8 °C in the dark., clear to slightly hazy, blue to purple
| | form | powder
| | color | blue-gray
| | Water Solubility | soluble | | Merck | 13,6236 | | Stability: | Stable. Incompatible with strong acids, strong bases, strong oxidizing agents. | | CAS DataBase Reference | 50-07-7(CAS DataBase Reference) | | EPA Substance Registry System | Azirino[2', 3':3,4]pyrrolo[1,2-a] indole-4,7-dione, 6-amino-8-[[(aminocarbonyl) oxy]methyl]-1,1a,2,8,8a,8b- hexahydro-8a-methoxy-5-methyl-, (1aS,8S,8aR,8bS)-(50-07-7) |
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[1aR-(1aalpha,8beta,8aalpha,8balpha)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-alpha]indole-4,7-dione
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SigmaAldrich
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| | Mitomycin C Usage And Synthesis |
| Chemical Properties | Blue-Violet Crystals | | Usage | An antitumor antibiotic. It is used as antineoplastic. | | Usage | Mitomycin C is the most studied of a family of highly distinctive blue/purple metabolites produced by several Streptomyces species. Mitomyin C exhibits potent antibacterial and antitumour activity and inhibits DNA synthesis by intercalation, blocking nuclear division with the induction of apoptosis in cancer cells. | | Usage | Mitomycin C is the most studied of a family of highly distinctive blue/purple metabolites produced by several Streptomyces species. Mitomycin C exhibits potent antibacterial and antitumor activity and inhibits DNA synthesis by intercalation, blocking nuclear division with the induction of apoptosis in cancer cells. | | General Description | Blue-violet crystals. Used as an anti-tumor antibiotic complex. | | Air & Water Reactions | Water soluble. | | Reactivity Profile | Mitomycin C is sensitive to prolonged exposure to light. Mitomycin C may be sensitive to prolonged exposure to air. Mitomycin C is incompatible with strong oxidizing agents, strong acids and strong bases. Calcium salts may cause decomposition. | | Health Hazard | Toxic doses as low as 750 mg/kg have been reported in humans. The major toxic effect is myelosuppression, characterized by marked leukopenia and thrombocytopenia; this may be delayed and cumulative. Interstitial pneumonia and glomerular damage resulting in kidney failure are unusual but well documented complications. Lung conditions -- administration of mitomycin has been recognized as causing pneumonitis, alveolitis and pulmonary fibrosis. Kidney conditions -- administration of Mitomycin Can cause kidney damage. Kidney toxicity was observed in 1-5 percent of patients. Depressed immune conditions. | | Fire Hazard | Flash point data for Mitomycin C are not available; however, Mitomycin C is probably combustible. | | Biological Activity | Antibiotic and antitumor agent. Covalently binds DNA forming intra- and interstrand crosslinks. Inhibits DNA synthesis. |
| | Mitomycin C Preparation Products And Raw materials |
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