| Identification | More | 【Name】
AG 490 | 【CAS】
134036-52-5 | 【Synonyms】
2-CYANO-3-[3,4-DIHYDROXYPHENYL]-N-[PHENYLMETHYL]-2-PROPENAMIDE
A-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMAMIDE
A-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE
AG 490
ALPHA-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE
(E)-2-CYANO-3-(3,4-DIHYDROPHENYL)-N-(PHENYLMETHYL)-2-PROPENAMIDE
N-BENZYL-3,4-DIHYDROXY-ALPHA-CYANOCINNAMIDE
N-BENZYL-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE
TYROPHOSTIN AG490
TYRPHOSTIN AG 490
TYRPHOSTIN B42
TYRPHOSTIN AG 490, 99+%
2-Cyano-3-(3,4-dihydroxyphenyl)-N-benzylacrylamide
N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)propenamide | 【Molecular Formula】
C17H14N2O3 | 【MDL Number】
MFCD00209833 | 【Molecular Weight】
294.3 | 【MOL File】
134036-52-5.mol |
| Chemical Properties | Back Directory | 【Appearance】
Pale Yellow-Green Crystal | 【mp 】
215 | 【storage temp. 】
−20°C
| 【solubility 】
ethanol: 5 mg/mL
| 【form 】
solid
| 【color 】
yellow
| 【Usage】
A potent and specific inhibitor of the Jak-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. AG-490 does not si | 【CAS DataBase Reference】
134036-52-5(CAS DataBase Reference) |
| Safety Data | Back Directory | 【Hazard Codes 】
Xi | 【Risk Statements 】
R36/37/38:Irritating to eyes, respiratory system and skin . | 【Safety Statements 】
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | 【WGK Germany 】
1
| 【Hazard Note 】
Irritant/Keep Cold under -20C |
|
| Company Name: | Shanghai Boyle Chemical Co., Ltd.
|
| Telephone: | Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market) |
| Contact Fax: | 86-21-57758967 |
| Website: | www.boylechem.com |
| Company Name: | J & K SCIENTIFIC LTD.
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| Telephone: | 400-666-7788 +86-10-82848833 |
| Contact Fax: | +86-10-82849933 |
| Website: | www.jkchemical.com |
| Company Name: | GIHI CHEMICALS CO.,LTD
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| Telephone: | 0086-571-86217390 |
| Contact Fax: | 0086-571-86217391 |
| Website: | www.gihichem.com |
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