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50-18-0

50-18-0 Structure

50-18-0 Structure
IdentificationMore
【Name】

Cyclophosphamide
【CAS】

50-18-0
【Synonyms】

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate
2-(Bis(2-chloroethyl)amino)-2H-1,3,2-oxazaphosphorine 2-oxide
2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide
2-H-1,3,2-Oxazaphosphorinane
2H-1,3,2-Oxazaphosphorine, 2-(bis(2-chloroethyl)amino)tetrahydro-,2-oxide
2H-1,3,2-Oxazaphosphorine, 2-(bis(2-chloroethyl)amino)tetrahydro-,2-oxide, monohydrate
ASTA
Asta B 518
B 518
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
CB 4564
Clafen
Claphene
CY
Cyclophosphamid
Cyclophosphamidum
Cyclophosphan
Cyclophosphane
Cyclophosphoramide
Cyclostin
【EINECS(EC#)】

200-015-4
【Molecular Formula】

C7H15Cl2N2O2P
【Molecular Weight】

261.086
【MOL File】

50-18-0.mol
Chemical PropertiesBack Directory
【Appearance】

white crystalline powder
【mp 】

41-45°C
【Stability:】

Stable, but light sensitive. Incompatible with oxidizing agents.
【Water Solubility 】

Soluble. 1-5 g/100 mL at 23 ºC
【CAS DataBase Reference】

50-18-0(CAS DataBase Reference)
【NIST Chemistry Reference】

2-[Bis(2-chloroethylamino)]-tetrahydro-2h-1,3,2-oxazaphosphorine-2-oxide(50-18-0)
【EPA Substance Registry System】

50-18-0(EPA Substance)
Safety DataBack Directory
【Safety Statements 】

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
【RIDADR 】

UN 1851
【HazardClass 】

6.1(b)
【PackingGroup 】

III
【Hazardous Substances Data】

50-18-0(Hazardous Substances Data)
Hazard InformationBack Directory
【General Description】

Fine white crystalline powder. Odorless with a slightly bitter taste. Melting point 41-45°C. A 2% solution has pH of 4 to 6. Used medicinally as an antineoplastic agent.
【Reactivity Profile】

CYCLOPHOSPHAMIDE(50-18-0) is sensitive to exposure to light (darkens). Also sensitive to oxidation. Aqueous solutions may be kept for a few hours at room temperature, but hydrolysis occurs at temperatures above 86°F. Solutions in DMSO, 95% ethanol or acetone are stable for 24 hours under normal lab conditions. Incompatible with benzyl alcohol. Undergoes both acid and base hydrolysis at extreme pHs
【Air & Water Reactions】

Water soluble.
【Fire Hazard】

Flash point data for this chemical are not available; however, CYCLOPHOSPHAMIDE is probably combustible.
Material Safety Data Sheet(MSDS)Back Directory
【msds information】

Cyclophosphamide(50-18-0).msds
Well-known Reagent Company Product InformationBack Directory
【Sigma Aldrich】

50-18-0(sigmaaldrich)
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