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N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamid, (E)- Produkt Beschreibung

CAS-Nr.404-86-4
Bezeichnung:N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamid, (E)-
Englisch Name:Capsaicin
Synonyma:Capsaisin;N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamid, (E)-
Halt;Zacin;Adlea;Axsain;Mioton;Zostrix;CAPSAICIN;FEMA 2787;FEMA 3404;CAPSAICINE
CBNumber:CB6112967
Summenformel:C18H27NO3
Molgewicht:305.41
MOL-Datei:404-86-4.mol
N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamid, (E)- physikalisch-chemischer Eigenschaften
Schmelzpunkt:: 62-65 °C(lit.)
Siedepunkt:: 210-220 C
FEMA : 3404
Flammpunkt:: 113 °C
storage temp. : 2-8°C
solubility : H2O: insoluble
Wasserlöslichkeit: insoluble
Merck : 1768
Stabilität:: Stable. Incompatible with strong oxidizing agents.
CAS Datenbank: 404-86-4(CAS DataBase Reference)
EPA chemische Informationen: 6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl) methyl]-8-methyl-, (6E)-(404-86-4)
Sicherheit
Kennzeichnung gefährlicher: T,T+
R-Sätze:: 25-37/38-41-42/43-36/37/38
S-Sätze:: 22-26-28-36/39-45-36/37/39
RIDADR : UN 2811 6.1/PG 2
WGK Germany : 3
RTECS-Nr.: RA8530000
F : 10-21
HazardClass : 6.1(a)
PackingGroup : II
Giftige Stoffe Daten: 404-86-4(Hazardous Substances Data)

N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamid, (E)- Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
Off-White Crystalline Solid
Verwenden
A representative lot is a 5:1 E:Z mixture. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.
Verwenden
K channel blocker; multiple sclerosis therapy
Verwenden
analgesic (topical), depletes Substance P, neurotoxic
Verwenden
Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.
Verwenden
Capsaicin is used in many topical ointments used to relieve the pain of peripheral neuropathy (treatment of pain in the nerve endings near the surface of the skin).
R-Sätze Betriebsanweisung:
R25:Giftig beim Verschlucken.
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augenschäden.
R42/43:Sensibilisierung durch Einatmen und Hautkontakt möglich.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
S36/39:Bei der Arbeit geeignete Schutzkleidung und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Biologische Aktivit?t
Prototypic vanilloid receptor agonist (pEC 50 values are 7.97 and 7.10 at rat and human VR1 receptors respectively). Excites a subset of primary afferent sensory neurons, with subsequent antinociceptive and anti-inflammatory effects. Reversibly inhibits aggregation of platelets. Also available as part of the Vanilloid TRPV1 Receptor Tocriset™ .
N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamid, (E)- Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Natriumhydrid Tetrahydrofuran Trimethylphosphit Hydrogenchlorid Natriumhydroxid Hydroxylammoniumchlorid Vanillin Thionyldichlorid
Downstream Produkte
N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamid, (E)- Anbieter Lieferant Produzent Hersteller Vertrieb Händler.      Global( 211)Lieferanten     
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Wuhan Dahua Pharmaceutical Co., Ltd. 027-59262863027-5942098067055399@qq.comCHINA 4994 58
Nanjing Duolong Bio-tech Co.,Ltd. 025-83263139 18905173768025-8326313952513593@qq.comCHINA 1982 50
Shanghai Boyle Chemical Co., Ltd. Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)86-21-57758967sales@boylechem.comCHINA 5604 55
J & K SCIENTIFIC LTD. ----jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96847 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)sh@meryer.comCHINA 40407 62
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:1893055203786-21-5032810967055399@qq.comCHINA 15983 69
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TCI (Shanghai) Development Co., Ltd. ----info@chemicalbook.comCHINA 22159 81
Energy Chemical 021-58432009 / 400-005-6266021-58436166-800info@energy-chemical.comCHINA 44198 61
BePharm Ltd. (Click here for a quote) 40068-59117; 86-21-51816456-8021/8022/8023+86-21-51816740 (China Mainland); +86-21-51816457 (Others)product@bepharm.comCHINA 24999 61
 
404-86-4(N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamid, (E)-)Verwandte Suche:
Methylacrylat 2-HYDROXYACETAMIDE (Trifluormethoxy)benzol 3-Methoxybenzylalkohol Methan α-Tocopherol 3,6-Bis[(4-chlor-2-phosphonophenyl)azo]-4,5-dihydroxynaphthalin-2,7-disulfonsure Anisol Parathion-methyl (ISO) Methoxyessigsäure Thiophanat-methyl 4-Methoxy-anilin Methyl N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamid, (E)- Methyl-4-hydroxybenzoat Kresoxim-methyl Methylacetat Bensulfuron methyl
(E)-8-METHYL-NON-6-ENOIC ACID 4-HYDROXY-3-METHOXY-BENZYLAMIDE (E)-CAPSAICIN (E)-N-([4-HYDROXY-3-METHOXYPHENYL]METHYL)8-METHYL-6-NONEAMIDE (E)-N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6-NONENAMIDE CAPSAICIN CAPSAICINE CAPSAICIN, NATURAL FEMA 3404 FEMA 2787 8-METHYL-N-VANILLYL-TRANS-6-NONENAMIDE 8-METHYL-N-VANILLYL-6-NONENAMIDE 8-METHYL-N-VANILLYL-6-NONENEAMIDE 404-86-4 Carbonyl Compounds CA - CG Building Blocks Analytical Standards Biochemicals and Reagents BioChemical Amides Analytical Chromatography Product Catalog Alphabetic N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6E-NONENAMIDE N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6-NONENAMIDE TRANS-8-METHYL-N-VANILLYL-6-NONENAMIDE Lipids Organic Building Blocks Fatty Acids Others Saturated fatty acids and derivatives (e)-6-nonenamid capsaicin(fromoleoresinofcapsicum)plusrelatedcapsaicinoids n-(4-hydroxy-3-methoxybenzyl-8-methylnon-trans-6-enamide nci-c56564 trans-n-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide AMIDE Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. 8-METHYL-N-VANILLYL-6-NONENAMIDE*APPROX. 60% Capsaicin pure N-Vanillylnonenamide=Nonanoicacidvanillylamide C18H27NO3 8-METHYL-N-VANILLYL-6-NONENAMIDE NATUREL (6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide Axsain Mioton Zacin Zostrix 6-Nonenamide, N-(4-hydroxy-3-methoxyphenyl)methyl-8-methyl-, (6E)- CAPSAICINEXTRACT CAPSAICIN,NATURAL,USP CAPSAICIN,USP (E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide CAPSAICIN(USP28: 100% CAPSICUM EXTRACT) TRANS-CAPSAICIN INORGANIC & ORGANIC CHEMICALS (e)-6-nonenamide Anilines, Aromatic Amines and Nitro Compounds Miscellaneous Natural Products
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