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| CAS-Nr. | 94055-76-2 |
| Bezeichnung: | |
| Englisch Name: | Suplatast tosilate |
| Synonyma: |
IPD-1151T;Suplatast;Suplatast tosylate;SUPLATAST TOSILATE;2-[4-(2-Hydroxy-3-ethoxypropoxy)phenylcarbamoyl]ethyldimethylsulfonium;N-[4-(2-Hydroxy-3-ethoxypropoxy)phenyl]-3-(dimethylsulfonio)propanamide;[2-[4-(2-Hydroxy-3-ethoxypropoxy)phenylcarbamoyl]ethyl]dimethylsulfonium;[3-Oxo-3-[4-(2-hydroxy-3-ethoxypropoxy)phenylamino]propyl]dimethylsulfonium;[2-[[[4-(2-Hydroxy-3-ethoxypropoxy)phenyl]amino]carbonyl]ethyl]dimethylsulfonium;(2-(4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl)ethyl)dimethylsulfonium p-toluenesulfonate |
| CBNumber: | CB8837187 |
| Summenformel: | C23H33NO7S2 |
| Molgewicht: | 499.64062 |
| MOL-Datei: | 94055-76-2.mol |
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| Suplatast tosilate physikalisch-chemischer Eigenschaften |
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| storage temp. : |
Store at RT |
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Suplatast tosilate Chemische Eigenschaften,Einsatz,Produktion Methoden |
Verwenden
Suplatast Tosylate is an antiallergic drug. Suplatast Tosylate inhibits antigen-induced histamine release from mast cells as well as IgE antibody formation. Suplatast Tosylate suppresses interleukin (IL)-4 release from T cells, however in human peripheral basophils, Suplatast Tosylate inhibited the antigen-induced release of IL-13 but not IL-4. |
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Verwenden
Suplatast Tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM. |
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Biologische Aktivit?t
Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN- γ production. Acts as an immunoregulator that suppresses IgE production, eosinophil infiltration and histamine release. Exhibits antiasthmatic, anti-inflammatory and antifibrotic activity in vivo and is orally active. |
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| Suplatast tosilate Upstream-Materialien And Downstream Produkte |
Upstream-Materialien
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Downstream Produkte
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| Suplatast tosilate Anbieter Lieferant Produzent Hersteller Vertrieb Händler. Global( 57)Lieferanten |
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