Motesanib

CAS No.	453562-69-1
Chemical Name:	Motesanib
Synonyms:	D06678;motesanib;Motesanib Base;AMG-706(Motesanib);Motesanib (AMG-706) Base);N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide;N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide,AMG706;N-(3,3-diMethylindolin-6-yl){2-[(4-pyridylMethyl)-aMino](3-pyridyl)}-carboxaMide;N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide;3-PyridinecarboxaMide, N-(2,3-dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-
CBNumber:	CB01518524
Molecular Formula:	C22H23N5O
Formula Weight:	373.45
MOL File:	453562-69-1.mol

Motesanib Property

density :

1.251

Safety

Motesanib Chemical Properties,Usage,Production

Chemical Properties
Pale Yellow Solid

Usage
Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively.

Usage
Motesanib is an oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma.

Motesanib Preparation Products And Raw materials

Raw materials

Preparation Products

Motesanib Suppliers Global( 55)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
Beijing Kaida Technology Development Co., Ltd.	+86 (10) 5664-5598 / +86 13811060439	+86 (10) 62230033	bjkaida@163.com	CHINA	2000	59
Shanghai Boyle Chemical Co., Ltd.	Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)	86-21-57758967	sales@boylechem.com	CHINA	5604	55
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
ZHIWE CHEMTECH CO LTD	021-20221225;13917446399；QQ:2381298399		sales@zhiwe.net;zwchem@163.com	CHINA	297	61
Chembest Research Laboratories Limited	+86(0)21-20908456	+86(0)21-58180499	sales@biochembest.com	CHINA	6000	61
Chemfun Medical Technology(Shanghai) Co., Ltd.	021-67220633 & 021-37212706	+86-21-67220638	chemfun@chemfun.net	CHINA	21915	59
LGM Pharma	1-(800)-881-8210	615-250-9817	inquiries@lgmpharma.com	USA	1972	70
Nanjing Chemlin Chemical Co., Ltd	025-83697070; 010-68547217	+86-25-83453306	sales@chemlin.com.cn	CHINA	20120	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380		shchemsky@sina.com	CHINA	32553	50
Jinan Trio PharmaTech Co., Ltd.	+86 (531) 88811793；+86 (531) 88811783;+(0)18854807083;	+86 (531) 55696010 QQ981200479	sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)	CHINA	1779	62

453562-69-1(Motesanib)Related Search:

Motesanib Xylene Imiquimod Dacthal Dimethyl fumarate N,N-Dimethylformamide Dimethyl carbonate Dimethyl sulfoxide Dimethyl sulfate Dimethyl phthalate Dimethyl ether ETHANE

453562-69-1 motesanib N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide,AMG706 D06678 N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide N-(3,3-diMethylindolin-6-yl){2-[(4-pyridylMethyl)-aMino](3-pyridyl)}-carboxaMide 3-PyridinecarboxaMide, N-(2,3-dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]- Motesanib Base AMG-706(Motesanib) Antineoplastic Motesanib (AMG-706) Base)