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| CAS No. | 78111-17-8 |
| Chemical Name: | OKADAIC ACID |
| Synonyms: | OA;NSC 677083;Okadic acid;OKADAIC ACID;Ocadaic Acid;HALOCHONDRINE A;Okadaic acid,97%;35-Demethyl-DTX 1;OKADAIC ACID, 98+%;OKADAIC ACID, 25 UG* |
| CBNumber: | CB0246204 |
| Molecular Formula: | C44H68O13 |
| Formula Weight: | 805 |
| MOL File: | 78111-17-8.mol |
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| OKADAIC ACID Property |
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| solubility : |
DMSO: ≥1 mg/mL
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| Stability:: |
Stable. Light and heat-sensitive. Combustible. Incompatible with strong oxidizing agents. |
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OKADAIC ACID Chemical Properties,Usage,Production |
Chemical Properties
white crystals or powder |
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Usage
Okadaic acid is a widely distributed marine toxin produced by several phytoplanktonic species and responsible for diarrheic shellfish poisoning in humans. At the molecular level, Okadaic acid is a pot
ent and specific inhibitor of various types of serine/threonine protein phosphatases. Due to this enzymatic inhibition, Okadaic acid was reported to induce numerous alterations in relevant cellular ph
ysiological processes, including metabolic pathways such as glucose uptake, lipolysis and glycolysis, heme metabolism and glycogen and protein synthesis. |
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Biological Activity
Potent inhibitor of protein phosphatase 1 (IC 50 = 3 nM) and protein phosphatase 2A (IC 50 = 0.2-1 nM). Displays > 100,000,000-fold selectivity over PP2B and PP2C. Tumor promotor. Shown to activate atypical protein kinase C in adipocytes. |
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| OKADAIC ACID Preparation Products And Raw materials |
Raw materials
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Preparation Products
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| OKADAIC ACID Suppliers Global( 54)Suppliers |
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OA
OKADAIC ACID, PROROCENTRUM CONCAVUM
OKADAIC ACID
P to Q
Protein phosphatase-1, Catalytic Subunit
Protein Phosphatase 1 (PP1)
Kinase/Phosphatase Biology
Substrate Analogs
Serine/Threonine Phosphatase Inhibitors
Enzymes, Inhibitors, and Substrates
Enzyme Inhibitors by Enzyme
Enzyme Inhibitors by Type
Enzyme Inhibitors
BioChemical
Biochemicals and Reagents
Cell Signaling and Neuroscience
Cell Biology
9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN
9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIOFOLICIN
78111-17-8
HALOCHONDRINE A
9,10-deepithio-9,10-didehydro-acanthifolici
OKADAIC ACID >95% PROTEIN PHOSPHATASE I
OKADAIC ACID AMMONIUM SALT WATER-SOLUBLE ANALOG
OKADAIC ACID FREE ACID
OKADAIC ACID, 25 UG*
OKADAIC ACID FROM PROROCENTRUM SP.
OKADAIC ACID SODIUM SALT 98+%
OKADAIC ACID, 98+%
C44H68O13
Okadaicacid,Prorocentrumconcavum,highpurity
1,7-Dioxaspiro5.5undec-10-ene-2-propanoic acid, .alpha.,5-dihydroxy-.alpha.,10-dimethyl-8-(1R,2E)-1-methyl-3-(2R,4aR,5R,6S,8R,8aS)-octahydro-8-hydroxy-6-(1S,3S)-1-hydroxy-3-(2S,3R,6S)-3-methyl-1,7-dioxaspiro5.5undec-2-ylbutyl-7-methylenespirofuran-2(3H),2
OKADAICACID,HIGHPURITY
Protein Phosphatase
9,45-Seco-10-demercapto-9,10-didehydroacanthifolicin
Ocadaic Acid
Okadic acid
Okadaic acid,97%
Signalling
Blue mussel, homogenized (Okadaic acid)
Okadaic acid from Prorocentrum concavum,OA
Okadaic acid, free acid >98%
Natural Products
Inhibitor
35-Demethyldinophysistoxin 1
35-Demethyl-DTX 1
NSC 677083
1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(
Okadaic acid 35-Demethyl-DTX 1 NSC 677083 35-Demethyldinophysistoxin 1
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