SB218078

CAS No.	135897-06-2
Chemical Name:	SB218078
Synonyms:	9,10,11,12-Tetrahydro-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione
CBNumber:	CB51075435
Molecular Formula:	C24H15N3O3
Formula Weight:	393.401
MOL File:	135897-06-2.mol

SB218078 Property

storage temp. :

Store at RT

Safety

SB218078 Chemical Properties,Usage,Production

Biological Activity
Inhibitor of checkpoint kinase 1 (Chk1) that displays selectivity over other protein kinases (IC 50 values are 15, 250 and 1000 nM for Chk1, cdc2 and PKC respectively). Abrogates G 2 cell cycle arrest caused by γ -irradiation and topoisomerase I inhibition. Potentiates cytotoxicity of DNA-damaging drugs, enhancing the efficacy of some chemotherapeutics.

SB218078 Preparation Products And Raw materials

Raw materials

Preparation Products

SB218078 Suppliers Global( 5)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	86-21-50328103 * 801、802、803、804 Mobile:18930552037	86-21-50328109	67055399@qq.com	CHINA	15983	69
BOC Sciences	1-631-504-6093	1-631-614-7828	sales@bocsci.com	USA	9972	65
EMMX Biotechnology LLC	888-539-0666	888-539-0666	info@emmx.com	USA	8489	60

135897-06-2(SB218078)Related Search:

C-(9-ETHYL-9H-CARBAZOL-3-YL)-METHYLAMINE 1-(1-METHYL-1H-INDOL-4-YL)METHYLAMINE 97 SB218078 CARBAZOL-9-YL-METHANOL 1-ethyl-1H-indole-4-carbaldehyde N-METHYL-N-[(1-METHYL-1H-INDOL-5-YL)METHYL]AMINE 11,12-DIHYRDOINDOLO[2,3-A]CARBAZOLE 1-METHYL-1H-INDOLE-4-CARBALDEHYDE ARCYRIAFLAVIN A 4-AMINOMETHYLINDOLE N-Ethyl-3-carbazolecarboxaldehyde K-252C 1H-INDOLE-4-ETHANAMINE, N-METHYL-

135897-06-2 9,10,11,12-Tetrahydro-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione