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AG 490

CAS No.134036-52-5
Chemical Name:AG 490
Synonyms:AG 490;TYRPHOSTIN B42;TYROPHOSTIN AG490;TYRPHOSTIN AG 490;AG 490, Tryphostin B42;TYRPHOSTIN AG 490, 99+%;A-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE;N-BENZYL-3,4-DIHYDROXY-ALPHA-CYANOCINNAMIDE;A-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMAMIDE;ALPHA-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE
CBNumber:CB7779213
Molecular Formula:C17H14N2O3
Formula Weight:294.3
MOL File:134036-52-5.mol
AG 490 Property
mp : 215
storage temp. : −20°C
solubility : ethanol: 5 mg/mL
form : solid
color : yellow
CAS DataBase Reference: 134036-52-5(CAS DataBase Reference)
Safety
Hazard Codes : Xi
Risk Statements : 36/37/38-50-25
Safety Statements : 26-36-61-45
WGK Germany : 1
Hazard Note : Irritant/Keep Cold under -20C

AG 490 Chemical Properties,Usage,Production

Chemical Properties
Pale Yellow-Green Crystal
Usage
A potent and specific inhibitor of the Jak-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. AG-490 is cell permeable and is active in vivo.
AG 490 Preparation Products And Raw materials
Raw materials
Preparation Products
AG 490 Suppliers      Global( 40)Suppliers     
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Shanghai Boyle Chemical Co., Ltd. Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)86-21-57758967sales@boylechem.comCHINA 5604 55
J & K SCIENTIFIC LTD. ----jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96847 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:1893055203786-21-5032810967055399@qq.comCHINA 15983 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.comCHINA 32553 50
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333021-50323701sale@aladdin-e.comCHINA 24330 65
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969020-39119999isunpharm@qq.com, isunpharm@hotmail.comCHINA 4836 55
GIHI CHEMICALS CO.,LTD 0086-571-862173900086-571-86217391Sales@gihichem.comCHINA 885 58
Changzhou Renaissance Chem Co. Ltd 86-519-8620282186-519-82059043sales@rosewellchem.comCHINA 32 56
Credit Asia Chemical Co., Ltd. +86 (21) 61124340+86 (21) 6129-4103sales02@forever-reagent.comCHINA 9802 58
JiNan Weiran Biological Technology Co., Ltd. 13306417006; 18866807006; 0531-858689810531-85806006864598798@qq.comCHINA 503 50
 
134036-52-5(AG 490)Related Search:
AG 213 NS-398 N-Benzylacrylamide Tyrphostin AG 490 (N-benzyl-3,4-dihydroxy-benzylidenecyanoacetamide) (A) Tyrphostin AG 490 (N-benzyl-3,4-dihydroxy-benzylidenecyanoacetamide) AG 490 (Tyrphostin AG 490),AG 490,TYROPHOSTIN AG490,TYRPHOSTIN AG 490
(E)-2-CYANO-3-(3,4-DIHYDROPHENYL)-N-(PHENYLMETHYL)-2-PROPENAMIDE ALPHA-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE AG 490 A-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMAMIDE A-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE 2-CYANO-3-[3,4-DIHYDROXYPHENYL]-N-[PHENYLMETHYL]-2-PROPENAMIDE 134036-52-5 Cell Signaling and Neuroscience Cell Biology BioChemical N-BENZYL-3,4-DIHYDROXY-ALPHA-CYANOCINNAMIDE N-BENZYL-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE Kinase/Phosphatase Biology Janus Kinase (JAK) Non-Receptor Tyrosine Kinase Inhibitors TYRPHOSTIN AG 490 TYROPHOSTIN AG490 TYRPHOSTIN B42 TYRPHOSTIN AG 490, 99+% All Inhibitors Inhibitors Tyrosine Kinase Inhibitors 2-Cyano-3-(3,4-dihydroxyphenyl)-N-benzylacrylamide N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)propenamide Aromatics Intermediates & Fine Chemicals Pharmaceuticals AG 490, Tryphostin B42 34036-52-5 Inhibitor N-Benzyl-2-(3,4-dihydroxybenzylidene)-2-cyanoacetamide
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