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| CAS No. | 154447-35-5 |
| Chemical Name: | NU7026 |
| Synonyms: | LY 293646;2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one;2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one;4H-Naphtho[1,2-b]pyran-4-one, 2-(4-morpholinyl)-;2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one NU7026 |
| CBNumber: | CB8503981 |
| Molecular Formula: | C17H15NO3 |
| Formula Weight: | 281.31 |
| MOL File: | 154447-35-5.mol |
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| NU7026 Property |
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| solubility : |
DMSO: 3 mg/mL at 60 °C, soluble
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NU7026 Chemical Properties,Usage,Production |
Biological Activity
ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK). Displays selectivity over other PIKK family enzymes (IC 50 values are 0.23, 13.0, > 100 and > 100 μ M for DNA-PK, PI3K, ATM and ATR respectively). Radiosensitizes both proliferating and quiescent mouse embryonic fibroblast cells to IR and inhibits DSB repair. |
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| NU7026 Preparation Products And Raw materials |
Raw materials
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Preparation Products
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| NU7026 Suppliers Global( 27)Suppliers |
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