4,5,6,7-TETRABROMOBENZOTRIAZOLE

CAS No.	17374-26-4
Chemical Name:	4,5,6,7-TETRABROMOBENZOTRIAZOLE
Synonyms:	TBB;TBBT;NSC 231634;CK2 INHIBITOR;TBB(NSC 231634);TBB (enzyMe inhibitor);4,5,6,7-Tetrabromotriazole;CASEIN KINASE II INHIBITOR I;4,5,6,7-TETRABROMOBENZOTRIAZOLE;CASEIN KINASE II INHIBITOR TBB*
CBNumber:	CB9104424
Molecular Formula:	C6HBr4N3
Formula Weight:	434.71
MOL File:	17374-26-4.mol

4,5,6,7-TETRABROMOBENZOTRIAZOLE Property

mp :

262-266°C

storage temp. :

2-8°C

solubility :

DMSO: 28 mg/mL

form :

solid

color :

white

Safety

WGK Germany :

4,5,6,7-TETRABROMOBENZOTRIAZOLE Chemical Properties,Usage,Production

Chemical Properties
Crystalline Solid

Usage
TBB is one of the most selective protein kinase inhibitors known, and when tested against a panel of 33 serine/threonine and tyrosine protein kinases, only three exhibited moderate inhibition by TBB, with Ki values one to two orders of magnitude higher than that for CK2.

Biological Activity
A cell-permeable, selective inhibitor of casein kinase-2 (CK2) (IC 50 = 0.9 and 1.6 μ M for rat liver and human recombinant CK2 respectively). Exhibits modest discrimination between CK2 subunits, with K i values ranging from 80 nM to 210 nM. Acts in an ATP/GTP-competitive manner and displays one to two orders of magnitude selectivity over a panel of 33 protein kinases.

4,5,6,7-TETRABROMOBENZOTRIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

4,5,6,7-TETRABROMOBENZOTRIAZOLE Suppliers Global( 35)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
3B Pharmachem (Wuhan) International Co.,Ltd.	86-21-50328103 * 801、802、803、804 Mobile:18930552037	86-21-50328109	67055399@qq.com	CHINA	15983	69
Chemfun Medical Technology(Shanghai) Co., Ltd.	021-67220633 & 021-37212706	+86-21-67220638	chemfun@chemfun.net	CHINA	21915	59
Nanjing Chemlin Chemical Co., Ltd	025-83697070; 010-68547217	+86-25-83453306	sales@chemlin.com.cn	CHINA	20120	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380		shchemsky@sina.com	CHINA	32553	50
BOC Sciences	1-631-504-6093	1-631-614-7828	sales@bocsci.com	USA	9972	65
Nanjing JinruiJiuAn Biotechnology Co., Ltd.	025-58196018 QQ：800028039	025-83453306	sales@fartop.net	CHINA	2234	55
Shanghai Haoyuan Chemexpress Co., Ltd	86-21-58998590	86-21-53700326, 86-21-58998590	sales@chemexpress.cn	CHINA	10011	61
TCI Japan	03-3668-0489	03-3668-0520	sales@tokyokasei.co.jp	JAPAN	24828	80
TCI Europe	+32 (0)3 735 07 00	+32 (0)3 735 07 01	sales@tcieurope.eu	Europe	24334	75

17374-26-4(4,5,6,7-TETRABROMOBENZOTRIAZOLE)Related Search:

CASEIN KINASE II 5-BROMO-1H-BENZOTRIAZOLE 4,5,6,7-TETRABROMOBENZOTRIAZOLE

NSC 231634 TBB TBBT Kinase/Phosphatase Biology Serine/Threonine Kinase Inhibitors Casein Kinase (CK) Cell Biology Cell Signaling and Neuroscience BioChemical 17374-26-4 4,5,6,7-TETRABROMO-2-AZABENZIMIDAZOLE 4,5,6,7-TETRABROMOBENZOTRIAZOLE CASEIN KINASE II INHIBITOR I CK2 INHIBITOR 4,5,6,7-Tetrabromotriazole C6HBr4N3 4,5,6,7-Tetrabromo-1H-benzotriazole 35-95-2 CASEIN KINASE II INHIBITOR *TBB** Protein Kinase Inhibitors and Activators 4,5,6,7-Tetrabromo-2-azabenzimidazole, 4,5,6,7-Tetrabromobenzotriazole, NSC 231634, TBBt C6HN3Br4 Protein Kinase 1H-Benzotriazole, 4,5,6,7-tetrabroMo- TBB (enzyMe inhibitor) PI3K/Akt/mTOR 4,5,6,7-TetrabroMo-1H-benzo[d][1,2,3]triazole TBB(NSC 231634)