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5-Hydroxyindole

CAS No.1953-54-4
Chemical Name:5-Hydroxyindole
Synonyms:5-INDOLOL;NSC 87503;INDOL-5-OL;1H-INDOL-5-OL;5-hdroxyindole;5-羟基吲哚(订作2-3周);5-HYDROXYINDOLE;hydroxy-5indole;Hydroxy-5 indole;Hydroxyindole,98%
CBNumber:CB9151600
Molecular Formula:C8H7NO
Formula Weight:133.15
MOL File:1953-54-4.mol
5-Hydroxyindole Property
mp : 106-108 °C(lit.)
storage temp. : 0-6°C
color : beige
Sensitive : Light Sensitive
BRN : 112349
CAS DataBase Reference: 1953-54-4(CAS DataBase Reference)
NIST Chemistry Reference: Indol-5-ol(1953-54-4)
Safety
Hazard Codes : Xi
Risk Statements : 36/37/38
Safety Statements : 26-36-37/39
WGK Germany : 3
RTECS : NM2430000
HazardClass : IRRITANT, KEEP COLD
HS Code : 29339990

5-Hydroxyindole Chemical Properties,Usage,Production

Chemical Properties
beige to brown crystalline needles or powder
Usage
• ;Reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl)benzenesulfonates as antitumor agents and tubulin inhibitors1• ;Reactant for preparation of anthranilic acids2• ;Reactant for preparation of indole compounds as dopamine D2 receptor antagonists3• ;Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands4• ;Reactant for preparation of melanins as nature-inspired radioprotectors5• ;Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors6
Usage
5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptop han (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.
5-Hydroxyindole Preparation Products And Raw materials
Raw materials
3-Methyl-4-nitrophenol Red prussiate Palladium Benzyl bromide N,N-Dimethylformamide dimethyl acetal
Preparation Products
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5-Hydroxy-1H-indole Hydroxy-5 indole hydroxy-5indole Indoles Simple Indoles Heterocyclic Building Blocks TIMTEC-BB SBB004214 Building Blocks 1953-54-4 1H-INDOL-5-OL 5-HYDROXYINDOLE 5-INDOLOL INDOL-5-OL Hydroxyindole,98% 1593-54-4 1953-94-4 blocks IndolesOxindoles 5-hdroxyindole indole derivative Indoles and derivatives 5-HYDROXYINDOLE 99% pharmacetical Indole Indoles 5-Hydroxyindole, 98+% Simple Indoles 5-HYDROXYINDOLE (5OHI) 5-Hydroxyindole,97% 5-羟基吲哚(订作2-3周) 5-Hydroxyindole,5-Hydroxyindole, 5-Indolol 5-Hydroxyindole, 97% 1GR NSC 87503 Building Blocks C7 to C9 Chemical Synthesis Heterocyclic Building Blocks 5-Hydroxyindoline Heterocycle-Indole series
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