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ベルルクロゲンTR1

CAS番号.12771-72-1
化学名:ベルルクロゲンTR1
别名:ベルクロゲン;ベルルクロゲン;ベルクロゲンTR1;ベルクロゲンTR-1;ベルルクロゲンTR1
英語化学名:VERRUCULOGEN
英語别名:tr1;T1R1;TRXR1;GPR70;TAS1R1;NA 209A;GRIM-12;MGC9145;TR-1TOXIN;VERRUCOLOGEN
CBNumber:CB0294003
分子式:C27H35N3O7
分子量:513.58
MOL File:12771-72-1.mol
ベルルクロゲンTR1 物理性質
貯蔵温度 : 2-8°C
安全性情報
主な危険性 : T,Xn,F
Rフレーズ : 23/24/25-36-20/21/22-11
Sフレーズ : 36/37/39-45-36/37-26-16
RIDADR : UN 2811 6.1/PG 2
WGK Germany : 3
RTECS 番号: JH4920000

ベルルクロゲンTR1 化学特性,用途語,生産方法

使用
Verruculogen is a tremorgenic mycotoxin, first isolated from Penicillium verruculosum in 1972. The structure was resolved as an indole alkaloid in 1974. Verruculogen is produced by several species of Penicillium and Aspergillus and its presence is a useful taxonomic phenotypic marker. The tremorgenic action of verruculogen is associated with increases in spontaneous glutamate and aspartate release, decreases in GABA levels and, at toxic doses, an increase in the number and decrease in the affinity of DHP receptors in rat cortex. In in vitro guinea pig ileum preparations, verruculogen causes an increase in contractile responses due to electrical field stimulation, attributed to enhancement of acetylcholine from presynaptic nerve terminals. Verruculogen also inhibits Ca2+-activated K+ channels, and is a cell cycle inhibitor blocking division at the M phase.
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12771-72-1(ベルルクロゲンTR1) キーワード:
ベルルクロゲンTR1 2,5-ジメチルピペラジン (2S)-4-フェニル-2-ブタンアミン N,N-ビス(1-メチルエチル)アセトアミド 3-エチルアミノ-4-メチルフェノール N,N-ジブチルアセトアミド N-(1-メチル-3-フェニルプロピル)バレルアミド グリシン無水物 N,N-ジプロピルプロパンアミド 4-メチル-1-ピペラジンエタンアミン N,N-ジイソプロピルエチレンジアミン 1-ジブチルアミノ-2-プロパノール ピペリジン-2-メタンアミン 1,1-ジメチルプロピルヒドロペルオキシド
12771-72-1 VERRUCULOGEN VERRUCULOGEN, PENICILLIUM VERRUCULOSUM 3h)-dione,1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimeth 5h,12h-3,4-dioxa-5a,11a,15a-triazacyclooct(lm)indeno(5,6-b)fluorene-11,15(2h,1 tr1 verruculogentr1 yl-5-(2-methyl-1-propenyl)-,(5r-(5-alpha,10-alpha,10a-alpha,14a-alpha-15b-alp verruculogen from penicillium*verruculosum VERRUCULOGEN FROM PENICILLIUM VERRUCULOS VERRUCOLOGEN TR-1TOXIN (5R)-1,10,10a,14,14aα,15bα-Hexahydro-10α,10aα-dihydroxy-7-methoxy-2,2-dimethyl-5α-(2-methyl-1-propenyl)-12H-3,4-dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione (5R)-2,5,10,10a,11,12,13,14,14aα,15bα-Decahydro-10α,10aα-dihydroxy-7-methoxy-2,2-dimethyl-5α-(2-methyl-1-propenyl)-3,4-dioxa-5a,11a,15a-triaza-1H-cyclooct[lm]indeno[5,6-b]fluorene-11,15-dione (5R-(5alpha,10 alpha,10Aalpha,14aalpha,15balpha))-1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-5H,12H-3,4-dioxa-5A,11A,15A-triaza cyclooct (1m) indeno (5,6-B)fluorene-11,15(2H,13H)-dione 5H,12H-3,4-Dioxa-5A,11A,15A-triazacyclooct(lm)indeno(5,6-B)fluorene-11,15(2H,13H)-dione, 1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, (5R,10S,10ar,14as,15bs)- 5H,12H-3,4-Dioxa-5A,11A,15A-triazacyclooct(lm)indeno(5,6-B)fluorene-11,15(2H,13H)-dione, 1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-,(5R-(5-alpha,10-alpha,10A-alpha,14A-alpha-15B-alpha))- Verruculogenresearch grade NA 209A Verruculogen NA 209A TR 1 toxin Verruculogen solution GRIM-12 MGC9145 TRXR1 TXNRD1 human Anti-TAS1R1 (N-terminal) antibody produced in rabbit GPR70 T1R1 TAS1R1 ANTI-TAS1R1 (CENTER) antibody produced in rabbit Taste receptor type 1 member 1 ベルクロゲン ベルルクロゲン ベルクロゲンTR1 ベルクロゲンTR-1 ベルルクロゲンTR1
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