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(7S,13E,16R,20R,21E)-7,20-ジヒドロキシ-16-メチル-10-フェニル-24-オキサ[14]サイトカラサ-6(12),13,21-トリエン-1,23-ジオン

CAS番号.14930-96-2
化学名:(7S,13E,16R,20R,21E)-7,20-ジヒドロキシ-16-メチル-10-フェニル-24-オキサ[14]サイトカラサ-6(12),13,21-トリエン-1,23-ジオン
别名:ホミン;サイトカラシンB;シトカラシンB;(7S,13E,16R,20R,21E)-7,20-ジヒドロキシ-16-メチル-10-フェニル-24-オキサ[14]サイトカラサ-6(12),13,21-トリエン-1,23-ジオン
英語化学名:CYTOCHALASIN B
英語别名:PHOMIN;-23-one;cytochalasin;CYTOCHALACINB;CYTOCHALICINB;CYTOCHALASIN B;CYTOCHALASIN B(RG);(7s,13e,16r,20r,21e)-0-phenyl;CYTOCHALASIN B SYNTHETIC >97%;9r,12as,13s,15s,15as,16as,18as)-5
CBNumber:CB6323824
分子式:C29H37NO5
分子量:479.61
MOL File:14930-96-2.mol
(7S,13E,16R,20R,21E)-7,20-ジヒドロキシ-16-メチル-10-フェニル-24-オキサ[14]サイトカラサ-6(12),13,21-トリエン-1,23-ジオン 物理性質
融点 : 218-223 °C
貯蔵温度 : −20°C
solubility : ethanol: 20 mg/mL
外見 : powder
color : white
Merck : 13,2819
EPAの化学物質情報: 2H-Oxacyclotetradecino[ 2,3-d]isoindole-2,18(5H)- dione, 6,7,8,9,10,12a,13,14,15,15a, 16,17-dodecahydro-5,13-dihydroxy- 9,15-dimethyl-14-methylene- 16-(phenylmethyl)-, (3E,5R,9R,11E,12aS,13S,15S, 15aS,16S,18aS)-(14930-96-2)
安全性情報
主な危険性 : T+,T
Rフレーズ : 26/27/28-63-23/24/25
Sフレーズ : 28-36/37-45
RIDADR : UN 1544 6.1/PG 2
WGK Germany : 3
RTECS 番号: RO0205000
F : 10
国連危険物分類 : 6.1(a)
容器等級 : I
有毒物質データの: 14930-96-2(Hazardous Substances Data)

(7S,13E,16R,20R,21E)-7,20-ジヒドロキシ-16-メチル-10-フェニル-24-オキサ[14]サイトカラサ-6(12),13,21-トリエン-1,23-ジオン 化学特性,用途語,生産方法

化学的特性
white to off-white powder
使用
Cytochalasin B is one of the most extensively studied members of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, giving rise to pronounced morphogenic activity in animals and plants. Like most cytochalsins, cytochalasin B exhibits potent inhibition of actin filament function leading to cell death by apoptosis, and displays a broad range of resultant cellular actions. Despite the common mode of action, there is evidence that individual members of this class display diverse selectivity. However, lack of comparative co-metabolite analysis has restricted a more complete understanding of their individual selectivity.
使用
Cytochalasin B is one of the most extensively studied members of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, giving rise to pronounced morphogenic activity in animals and plants. Like most cytochalasins, cytochalasin B exhibits potent inhibition of actin filament function leading to cell death by apoptosis, and displays a broad range of resultant cellular actions. Despite the common mode of action, there is evidence that individual members of this class display diverse selectivity. However, lack of comparative co-metabolite analysis has restricted a more complete understanding of their individual selectivity.
(7S,13E,16R,20R,21E)-7,20-ジヒドロキシ-16-メチル-10-フェニル-24-オキサ[14]サイトカラサ-6(12),13,21-トリエン-1,23-ジオン 上流と下流の製品情報
原材料
準備製品
(7S,13E,16R,20R,21E)-7,20-ジヒドロキシ-16-メチル-10-フェニル-24-オキサ[14]サイトカラサ-6(12),13,21-トリエン-1,23-ジオン 生産企業      Global( 77)Suppliers     
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14930-96-2((7S,13E,16R,20R,21E)-7,20-ジヒドロキシ-16-メチル-10-フェニル-24-オキサ[14]サイトカラサ-6(12),13,21-トリエン-1,23-ジオン) キーワード:
(7S,13E,16R,20R,21E)-7,20-ジヒドロキシ-16-メチル-10-フェニル-24-オキサ[14]サイトカラサ-6(12),13,21-トリエン-1,23-ジオン 2-ヒドロキシイソブチルアミド アクリル酸1-メチルヘプチル アクリル酸シクロヘキシル 2-ブテン酸ヘプチル 2-ヘキセン酸エチル 2-ブテン酸tert-ブチル 1-アミノメチル-1-シクロヘキサノール塩酸塩 2-プロピルバレルアミド 2-メチル-4-ペンテン-2-オール=アセタート 2-ブテン酸3-メチルブチル (S)-(+)-1-シクロヘキシルエチルアミン (S)-(-)-2-メトキシプロピオンアミド trans-2-デセン酸エチル ω-オクタラクタム アクリル酸tert-ブチル 2-ブテン酸オクチル アクリル酸2-エチルヘキシル (モノマー)
14930-96-2 PHOMIN (7s,13e,16r,20r,21e)-0-phenyl (e,e)-(5s,9r,12as,13s,15s,15as,16s,18as)-16-benzyl-6,7,8,9,10,12a,13,14,15,15a ,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-,(e)-( ,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-,(e,e) ,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-2h-oxacyclotetrad -23-one 24-oxa(14)cytochalasa-6(12),13,21-triene-1,23-dione,7,20-dihydroxy-16-methyl-1 2h-oxacyclotetradec(2,3-d)isoindole-2,18(5h)-dione,16-benzyl-6,7,8,9,10,12a,13 3-d)isoindole-2,18(5h)-dione,16-benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-2h-oxacyclotetradec( 7,20-dihydroxy-10-phenyl-5,16-dimethyl-24-oxa-[14]cytochalas-6(12),13,21-trien 9r,12as,13s,15s,15as,16as,18as)-5 9r,12as,13s,15s,15as,16s,18as)--(5 cytochalasin ec[2,3-d]isoindole-2,18(5h)-dione (E,E)-16-BENZYL-6,7,8,9,10,12A,13,14,15,15A,16,17-DODECAHYDRO-5,13-DIHYDROXY-9,15-DIMETHYL-14-METHYLENE-2H-OXACYCLOTETRADE[2,3-D]ISOINDOLE-2,18(5H)-DIONE CYTOCHALASIN B, HELMINTHOSPORIUM DEMATIOIDEUM CYTOCHALASIN B 7(S),20(R)-dihydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E),21(E)-triene-1,23-dione CYTOCHALASIN B FROM DRESCHSLERA DEMATIOIDEA CYTOCHALASIN B SYNTHETIC >97% CYTOCHALASIN B FROM DRESCHSLERA DEMATIOIDEA, BIOCHEMIKA, >= 95.0% (HPLC) Cytochalasin beta,helminthosporium dematioideum cytochalasin b from drechslera dematioidea CYTOCHALASIN B(RG) CYTOCHALACINB CYTOCHALICINB CYTOCHALASIN B FROM HELMINTHOSPORIUM DEMATIODEUM (7S,13E,16R,20R,21E)-7,20-Dihydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13,21-triene-1,23-dione (7S),(20R)-Dihydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E),21(E)-triene-1,23-dione ホミン サイトカラシンB シトカラシンB (7S,13E,16R,20R,21E)-7,20-ジヒドロキシ-16-メチル-10-フェニル-24-オキサ[14]サイトカラサ-6(12),13,21-トリエン-1,23-ジオン マクロライド系抗生物質
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