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| | Caffeine Basic information |
| | Caffeine Chemical Properties |
| mp | 234-236.5 °C(lit.)
| | bp | 178°C | | density | 1.23 | | FEMA | 2224 | | Fp | 178°C | | storage temp. | 2-8°C
| | Water Solubility | 20 g/L (20 ºC) | | Sublimation | 178 ºC | | Merck | 14,1636 | | BRN | 17705 | | Stability: | Stable. Incompatible with strong acids, strong bases, strong oxidizing agents, iodine, silver salts, tannins. Weakly light sensitive in solution. | | CAS DataBase Reference | 58-08-2(CAS DataBase Reference) | | NIST Chemistry Reference | Caffeine(58-08-2) | | EPA Substance Registry System | 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl- (58-08-2) |
| | Caffeine Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Usage | Caffeine is a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants.
In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is a cardiac and respiratory stimulant; diuretic. Caffeine is toxic at sufficiently high doses. | | Usage | CNS stimulant
respiratory stimulant;adenosine receptors antagonist | | General Description | Odorless white powder or white glistening needles, usually melted together. Bitter taste. Solutions in water are neutral to litmus. Odorless. | | Air & Water Reactions | Efflorescent in air. Water soluble. | | Reactivity Profile | Caffeine may be hygroscopic. Aqueous solutions (1.12 mg/mL) are stable for three weeks at 41° F if protected from light. In normal room lighting and at room temperature, solutions are stable for 3 days. Solutions of Caffeine in water, DMSO, 95% ethanol or acetone should be stable for 24 hours under normal lab conditions. REACTIVITY: Caffeine may react with strong oxidizing agents. Caffeine is also incompatible with iodine, silver salts and tannins. Caffeine is a very weak base. Caffeine is decomposed by strong solutions of caustic alkalis. | | Fire Hazard | Flash point data for Caffeine are not available; however, Caffeine is probably combustible. | | Biological Activity | Central nervous system stimulant. Antagonist at A 1 and A 2A adenosine receptors and inhibitor of cyclic nucleotide phosphodiesterases. Mobilises calcium from intracellular stores and inhibits benzodiazepine binding to GABA receptors. |
| | Caffeine Preparation Products And Raw materials |
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