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872-50-4
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Thalidomide
Thalidomide Suppliers list
Company Name:
Shanghai TaoSu Biochemical Technology Co., Ltd.
Gold
Tel:
021-33632979
Email:
info@tsbiochem.com
Products Intro:
Product Name:Thalidomide
CAS:50-35-1
Purity:98% Package:2mg/298RMB
Company Name:
Amoi Yinghua biotechnology Co. Ltd.
Gold
Tel:
18605020825
Email:
amoiyh@126.com
Products Intro:
Product Name:Thalidomide
CAS:50-35-1
Purity:99% HPLC Package:100g;500g;1kg;5kg
Company Name:
J & K SCIENTIFIC LTD.
Tel:
400-666-7788 +86-10-82848833
Email:
jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro:
Product Name:ThalidoMide
CAS:50-35-1
Purity:98% Package:500Mg,5g
Company Name:
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:
86-21-50328103 * 801、802、803、804 Mobile:18930552037
Email:
67055399@qq.com
Products Intro:
Product Name:ThalidoMide;N-(2,6-dioxo-3-piperidinyl)phthaliMide
CAS:50-35-1
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name:
Chembest Research Laboratories Limited
Tel:
+86(0)21-20908456
Email:
sales@biochembest.com
Products Intro:
Product Name:ThalidoMide
CAS:50-35-1
Remarks:C14251
Thalidomide Basic information
Product Name:
Thalidomide
Synonyms:
(+/-)-2-(2,6-DIOXO-3-PIPERIDINYL)-1H-ISOINDOLE-1,3(2H)-DIONE
;
2-(2,6-DIOXO-3-PIPERIDINYL)-1H-ISO-INDOLE-1,3(2H)-DIONE
;
ALPHA-PHTHALIMIDOGLUTARIMIDE
;
3-PHTHALIMIDOGLUTARIMIDE
;
(+/-)-THALIDOMIDE
;
THALIDOMIDE
;
(+/-)-N-(2,6-DIOXO-3-PIPERIDINYL)PHTHALIMIDE
;
N-(2,6-DIOXO-3-PIPERIDINYL)PHTHALIMIDE
CAS:
50-35-1
MF:
C13H10N2O4
MW:
258.23
EINECS:
200-031-1
Product Categories:
Intermediates & Fine Chemicals
;
Pharmaceuticals
;
API's
;
Cytokine signaling
;
Signalling
;
Influenza Viruses
;
Angiogenesis and Metastasis
;
Inhibitor
;
ROCCAL
Mol File:
50-35-1.mol
Thalidomide Chemical Properties
mp
269-271°C
storage temp.
Store at RT
solubility
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.6 mg/mL
Water Solubility
<0.1 g/100 mL at 22 ºC
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference
50-35-1(CAS DataBase Reference)
NIST Chemistry Reference
Phthalimide, n-(2,6-dioxo-3-piperidyl)-(50-35-1)
EPA Substance Registry System
1H-Isoindole-1,3( 2H)-dione, 2-(2,6-dioxo-3-piperidinyl)- (50-35-1)
Safety Information
Hazard Codes
T
Risk Statements
46-61-21-25-62-22
Safety Statements
53-22-26-36/37/39-45
RIDADR
UN 2811 6.1/PG 3
WGK Germany
3
RTECS
TI4375000
HazardClass
6.1(b)
PackingGroup
III
Hazardous Substances Data
50-35-1(Hazardous Substances Data)
MSDS Information
Provider
Language
2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
English
SigmaAldrich
English
Thalidomide Usage And Synthesis
Chemical Properties
White Powder
Usage
antiinfective (topical)
Usage
Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.
General Description
Needles or white powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Organic amides/imides, such as Thalidomide, react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Fire Hazard
Flash point data for Thalidomide are not available; however, Thalidomide is probably combustible.
Biological Activity
Teratogen, sedative-hypnotic with inherent anti-inflammatory properties. A selective inhibitor of tumor necrosis factor α (TNF- α ) synthesis.
Thalidomide Preparation Products And Raw materials
Tag:
Thalidomide(50-35-1)
Related Product Information
2-[2,6-DIOXO-3-(TRIFLUOROMETHYL)PIPERIDIN-3-YL]-1H-ISOINDOLE-1,3(2H)-DIONE
(R)-(+)-THALIDOMIDE
Thalidomide
4,4-Piperidinediol hydrochloride
N-Hydroxyphthalimide
Bismaleimide
N-Methylphthalimide
O-Phthalimide
DIALIFOS
3-Nitrophthalimide
Polyamideimide
4-Aminophthalimide
Phthalhydrazide
DROPERIDOL
Succinimide
2,2,6,6-Tetramethyl-4-piperidinol
Diphenoxylate
4-Nitrophthalimide
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