| Company Name: | 3B Pharmachem (Wuhan) International Co.,Ltd. |
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| Products Intro: |
Product Name:T 0901317;N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoroMethyl)ethyl]phenyl]benzenesulfonaMide
CAS:293754-55-9
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g |
| Company Name: | ShangHai Biochempartner Co.,Ltd |
| Tel: | +86 13818785766，400-021-9906 |
| Email: | gaoqing@biochempartner.com |
| Products Intro: |
Product Name:T0901317
CAS:293754-55-9
Purity:98% |
| Company Name: | Shanghai Hekang Biotechnology Co., Ltd. |
| Tel: | +86-021-54173791 |
| Email: | youchemicals@gmail.com |
| Products Intro: |
Product Name:T0901317
CAS:293754-55-9
Purity:98+% Package:1,5,10,25,100,250,500, 1000g |
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| | T0901317 Basic information |
| Product Name: | T0901317 | | Synonyms: | N-(2,2,2-TRIFLUOROETHYL)-N-[4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL]BENZENESULFONAMIDE;T0901317;TO-901317;N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide;BenzenesulfonaMide, N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoroMethyl)ethyl]phenyl]-;T 1317 | | CAS: | 293754-55-9 | | MF: | C17H12F9NO3S | | MW: | 481.33 | | EINECS: | | | Product Categories: | PPAR and RXR Regulators;Cell Signaling and Neuroscience;Gene Regulation and Expression | | Mol File: | 293754-55-9.mol |  |
| | T0901317 Chemical Properties |
| | T0901317 Usage And Synthesis |
| Biological Activity | Potent, high affinity liver X receptor (LXR) agonist (EC 50 ~ 50 nM, Kd values are 7 and 22 nM for LXR- α and LRXR- β respectively). Upregulates expression of the ABCA1 gene associated with cholesterol efflux regulation and HDL metabolism. Decreases amyloid- β production in primary neurons in vitro . Displays an EC 50 of ~ 5 μ M for activation of bile acid farnesoid X receptors (FXRs); 10-fold more potent than natural FXR ligand chenodeoxycholic acid. |
| | T0901317 Preparation Products And Raw materials |
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