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Product Name:Trifluoroacetic acid, 99.5%, for biocheMistry
CAS:76-05-1
Purity:99.5% Package:25ML Remarks:ACROS 293810250 |
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Product Name:Trifluoroacetic acid
CAS:76-05-1
Purity:AR,99.0% Package:500ML,100ML,500G,2.5KG |
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Product Name:Trifluoroacetic acid
CAS:76-05-1
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| Products Intro: |
Product Name:Trifluoroacetic acid
CAS:76-05-1
Purity:99% Package:100g;1KG ;25kg |
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| | Trifluoroacetic acid Basic information |
| | Trifluoroacetic acid Chemical Properties |
| mp | -15 °C | | bp | 72.4 °C(lit.)
| | density | 1.535 g/mL at 25 °C(lit.)
| | vapor density | 3.9 (vs air)
| | vapor pressure | 97.5 mm Hg ( 20 °C)
| | refractive index | n20/D 1.3(lit.)
| | Fp | None | | storage temp. | 2-8°C
| | Water Solubility | miscible | | Sensitive | Hygroscopic | | Merck | 14,9681 | | BRN | 742035 | | Stability: | Stable. Incompatible with combustible material, strong bases, water, strong oxidizing agents. Non-combustible. Hygroscopic. May react violently with bases. | | CAS DataBase Reference | 76-05-1(CAS DataBase Reference) | | NIST Chemistry Reference | Acetic acid, trifluoro-(76-05-1) | | EPA Substance Registry System | Acetic acid, trifluoro-(76-05-1) |
| | Trifluoroacetic acid Usage And Synthesis |
| Chemical Properties | Colorless liquid | | Usage | Mainly used as an fluorine-containing intermediate in fine chemical, pharmaceutical, pesticide and dye. It is used as a raw material in the process of glass coating , sugar and polypeptide synthetic. It is used as a catalyst in esterification reaction and condensation reaction and a protective agent for hydroxyl and amino. | | General Description | A colorless fuming liquid with a pungent odor. Soluble in water and denser than water. Corrosive to skin, eyes and mucous membranes. Used to make other chemicals and as a solvent. | | Air & Water Reactions | Fumes in air. Soluble in water. | | Reactivity Profile | Trifluoroacetic acid is a strong acid; attacks many metals [Handling Chemicals Safely 1980. p. 935]. A 30% solution of hydrogen peroxide in Trifluoroacetic acid is often used to destructively oxidize aromatic rings in preference to the side chains. Explosions have occurred, if the excess peroxide is not catalytically destroyed, prior to removal of solvent, [Tetrahedron Lett., 1977, 1703-1704]. The reduction of amides of Trifluoroacetic acid with lithium aluminum hydride are dangerous at all phases of the process, explosions have occurred, [Chem. Eng. News, 1955, 33, 1368]. | | Health Hazard | TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. | | Fire Hazard | Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. |
| | Trifluoroacetic acid Preparation Products And Raw materials |
| Preparation Products | PYRIDIN-3-YLMETHYL-HYDRAZINE-->PYRIDIN-4-YLMETHYL-HYDRAZINE-->1-(3-PYRROLIDINOPROPYL)PIPERAZINE-->Ceftibuten-->Octreotide acetate-->Ziprasidone-->Arbekacin-->(S)-2-Methylproline-->1-TERT-BUTYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-->4-CHLORO-6-HYDRAZINO-PYRIMIDIN-5-YLAMINE-->4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE-->2-(4-PENTYLBENZOYL)-1-BENZOFURAN-5-CARBALDEHYDE-->5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-->5-AMINO-6-CHLORO-PYRIMIDIN-4-OL-->1-TERT-BUTYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-->4-AMINO-2,6-DIBROMOPYRIDINE-->3-BROMO-5-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE-->2,2,2-TRIFLUORO-1-(3-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)ETHANONE-->FENPICLONIL-->LIMAPROST-->Pravastatin-->Cefcapene pivoxil-->2-(4-FLUOROBENZOYL)-1-BENZOFURAN-5-CARBALDEHYDE-->1H-PYRROLO[2,3-B]PYRIDINE, 4-NITRO--->4-bromo-2-(trifluoromethyl)quinoline-->1,7-DIDEAZAADENINE-->Cefteram pivoxil-->Quinapril-->4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE-->2-(4-BROMOBENZOYL)-1-BENZOFURAN-5-CARBALDEHYDE-->1H-Pyrrolo[2,3-b]pyridine, 4-nitro-, 7-oxide-->Alacepril-->2-(4-CHLOROBENZOYL)-1-BENZOFURAN-5-CARBALDEHYDE-->2,4,6-Trichloropyridine-->1,2,3,9-Tetrahydro-4(H)-carbazol-4-one-->Cefbuperazone-->LAZABEMIDE-->Isepamicine-->Lisinopril-->Methyl trifluoroacetate | | Raw materials | Acetic anhydride-->Hydrofluoric acid-->Benzotrifluoride-->Trifluoropropene-->Trichloroacetonitrile-->Trifluoroacetonitrile-->2,3-DICHLOROHEXAFLUORO-2-BUTENE |
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