4-Acetamidophenol

4-Acetamidophenol Property

mp : 168-172 °C(lit.) density : 1,293 g/cm3 Fp : 11 °C storage temp. : Store at RT Water Solubility : 14 g/L (20 ºC) Merck : 14,47 BRN : 2208089 CAS DataBase Reference: 103-90-2(CAS DataBase Reference) NIST Chemistry Reference: Acetaminophen(103-90-2) EPA Substance Registry System: Acetamide, N-(4-hydroxyphenyl)-(103-90-2)

Safety

Hazard Codes : Xn,T,F Risk Statements : 22-36/37/38-52/53-36/38-40-39/23/24/25-23/24/25-11 Safety Statements : 26-36-61-37/39-22-45-36/37-16-7 WGK Germany : 1 RTECS : AE4200000 HS Code : 29242930 Hazardous Substances Data: 103-90-2(Hazardous Substances Data)

4-Acetamidophenol Chemical Properties,Usage,Production

Chemical Properties White Solid Usage antiinfectant Usage dispersing agent in liquid scintillation counting Usage Analgesic; antipyretic General Description Odorless white crystalline solid. Bitter taste. pH (saturated aqueous solution) about 6. Air & Water Reactions Slightly soluble in water. Reactivity Profile 4-Acetamidophenol is sensitive to light. Incompatible with strong oxidizers. . Fire Hazard Flash point data for 4-Acetamidophenol are not available; however, 4-Acetamidophenol is probably combustible. Biological Activity Cyclooxygenase inhibitor; may be selective for COX-3 (IC 50 values are 460, > 1000 and > 1000 μ M for canine COX-3, and murine COX-1 and COX-2 respectively). Widely used analgesic and antipyretic agent.

4-Acetamidophenol Preparation Products And Raw materials

Raw materials Benzophenone hydrazone Acetic anhydride 4-Aminophenol Sodium bisulfite 4'-Hydroxyacetophenone Hydrochloric acid Acetic acid glacial Iron Magnesium oxide Activated carbon Sodium metabisulfite

Preparation Products 4-(Acetylamino)phenyl chloroacetate Oxibendazole ETHYL 5-BENZYLOXYINDOLE-2-CARBOXYLATE 6-ACETAMIDOCHROMAN-4-ONE 4-(ACETYLAMINO)PHENOXYACETIC ACID ETHYL ESTER BETA-(4-(ACETYLAMIDO)PHENOXY)PROPANOIC ACID Cefoperazone diamfenetide Phenacetin N-(4-(OXIRANYLMETHOXY)-1,2-EPOXYPROPANE 6-Fluoro-4-chromanone 4-ISOTHIOCYANATO-4'-NITRODIPHENYL ETHER

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