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CAS No. | 67-66-3 |
Chemical Name: | Chloroform |
Synonyms: | r20;TCM;R 20;CHCl3;HCC20;freon20;Freon 20;CHLOROFORM;SOLVENT MC;NCI-C02686 |
CBNumber: | CB5413313 |
Molecular Formula: | CHCl3 |
Formula Weight: | 119.38 |
MOL File: | 67-66-3.mol |
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Chloroform Property |
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density : |
1.492 g/mL at 25 °C(lit.)
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vapor density : |
4.1 (vs air)
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vapor pressure : |
160 mm Hg ( 20 °C)
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refractive index : |
n20/D 1.445(lit.)
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Water Solubility : |
8 g/L (20 ºC) |
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Chloroform Chemical Properties,Usage,Production |
Chemical Properties
Colorless liquid |
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Usage
Suitable for HPLC, spectrophotometry, environmental testing |
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Usage
Meets ACS specifications. |
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Usage
Facilitates recovery of the aqueous phase of PCRs which have been overlaid with mineral oil. |
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General Description
A clear colorless liquid with a characteristic odor. Denser (12.3 lb / gal) than water and slightly soluble in water. Hence sinks in water. Nonflammable under most conditions, but burns under extreme conditions. May cause illness by inhalation, skin absorption or ingestion. Used as a solvent, to make other chemicals, as a fumigant. |
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Air & Water Reactions
Slightly soluble in water. Dissolves in water to form a corrosive solution of hypochlorous acid which decomposes on standing to chlorine, oxygen, and chloric acid. |
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Reactivity Profile
A mixture of acetone and Chloroform in a residue bottle exploded. Since addition of acetone to Chloroform in the presence of base will result in a highly exothermic reaction, Chloroform is thought that a base was in the bottle. [MCA Case History 1661(1970)]. Powdered aluminum and carbon tetrachloride(also methyl chloride and Chloroform or mixtures of these chemicals) exploded when heated(to 153°C.) and by impact, [Chem. Eng. News 32:258(1954); UL Bull. Research 34(1945), ASESB Pot. Incid. 39(1968)]. An inadequately cooled addition of sodium to a Chloroform-methanol mixture (sodium methoxide) caused a violent explosion, [MCA Case History No. 693]. Chloroform is incompatible with dinitrogen tetraoxide, fluorine, sodium metal and alcohols, nitromethane, and triisopropylphosphine. |
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Health Hazard
Chloroform is classified as moderately toxic. Probable oral lethal dose for humans is 0.5 to 5 g/kg (between 1 ounce and 1 pint) for a 150 lb. person. The mean lethal dose is probably near 1 fluid ounce (44 g). It is a human suspected carcinogen. Also, it is a central nervous system depressant and a gastrointestinal irritant. It has caused rapid death attributable to cardiac arrest and delayed death from liver and kidney damage. |
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Fire Hazard
Container may explode in the heat of fire. When heated Chloroform liberates phosgene, hydrogen chloride, chlorine and toxic and corrosive oxides of carbon and chlorine. Chloroform explodes when in contact with aluminum powder or magnesium powder or with alkali metals (e.g., lithium, sodium, and potassium) and dinitrogen tetroxide. Chloroform reacts vigorously with acetone in the presence of potassium hydroxide or calcium hydroxide. Chloroform is oxidized by strong oxidizers such as chromic acid forming phosgene and chlorine. Chloroform reacts vigorously with triisopropylphosphine. Chloroform develops acidity from prolonged exposure to air and light. |
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Chloroform Preparation Products And Raw materials |
Raw materials
Chloral
2,2,2-TRICHLORO-1-ETHOXYETHANOL
Calcium oxide
Chlorine
Hydrochloric acid
Methanol
Sodium hydroxide
Calcium hypochlorite
Calcium hydroxide
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Preparation Products
BETA-BUTYROLACTONE
4-BIPHENYLSULFONYL CHLORIDE
2,2'-OXYDIACETYL CHLORIDE
2-Chloro-5-chloromethylthiazole
N-Methyl-4-pyridinamine
2-ETHOXYPHENYL ISOTHIOCYANATE
1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL
2-Diazo-1-naphthol-5-sulfonyl chloride
Ethyl 3-(N,N-dimethylamino)acrylate
3-CHLORO-2-METHYLPHENYL ISOTHIOCYANATE
3-Fluoro-4-hydroxybenzaldehyde
3-Ethoxyphenol
biocide agent C-38
Acipimox
4-(METHYLSULFINYL)PHENOL
3,5-DIMETHYLPHENYL ISOTHIOCYANATE
1-[(4-Methylphenyl)sulfonyl]-1H-imidazole
N-Heptafluorobutyrylimidazole
2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL ISOTHIOCYANATE
2-Bromo-2',4'-dichloroacetophenone
SULFUR TRIOXIDE TRIMETHYLAMINE COMPLEX
4-SULFAMIDOBENZOYL CHLORIDE DMF COMPLEX
PYRIPROPANOL
N-ethoxycarbonyl N,N′,N′-trimethyl guanidine
N-FORMYLGLYCINE ETHYL ESTER
orange yellow
(1R,3S)-1,2,2-trimethyl-1,3-cycloperltanediamine
poly (3-alkyl thiophene) fiber
1-ETHYL-3-METHYLIMIDAZOLIUM BIS(TRIFLUOROMETHYLSULFONYL)IMIDE, 99% [EMIIM]
2-Amino-5-bromothiazole monohydrobromide
DIBENZYL SULFOXIDE
TERT-BUTYL ISOCYANIDE
PYRROLIDONE HYDROTRIBROMIDE
2,4-Dichlorobenzenesulfonyl chloride
3,5-DIMETHOXYPHENYL ISOTHIOCYANATE
DIMETHYL 2,6-PYRIDINEDICARBOXYLATE
4-N-BUTYLTOLUENE
5-BROMO-2-(MORPHOLIN-4-YL)PYRIMIDINE
4-CHLORO-2-METHYLPHENYL ISOTHIOCYANATE
2-CHLORO-4-METHYLPHENYL ISOTHIOCYANATE
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Chloroform Suppliers Global( 0)Suppliers |
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