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COMBRETASTATIN A-4

CAS No.117048-59-6
Chemical Name:COMBRETASTATIN A-4
Synonyms:CA4;CS-A4;Combrestatin A4;CoMbretastatin A;Combretastatin A4;(Z)-CombretastatinA4;CA-4, Combretastatin A-4;combretastatin A-4 (CA-4);(Z)-2-Methoxy-5-(3,4,5-Trimethoxystyryl)Phenol;(Z)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol
CBNumber:CB9496826
Molecular Formula:C18H20O5
Formula Weight:316.3484
MOL File:117048-59-6.mol
COMBRETASTATIN A-4 Property
mp : 84.5-85.5°C
storage temp. : Desiccate at -20°C
Safety
Hazard Codes : T
Risk Statements : 23/24/25-41
Safety Statements : 26-36/37-39-45
RIDADR : UN 2811

COMBRETASTATIN A-4 Chemical Properties,Usage,Production

Chemical Properties
Crystalline Powder
Usage
Combretastatin is a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage. A potent cytotoxic agent which strongly inhibits the polymerization of tubulin by binding to the colchicine site.
Biological Activity
Antitumor, antiangiogenic and antimetastatic agent, in vitro and in vivo . Acts by inhibiting tubulin polymerization (IC 50 = 2-3 μ M).
COMBRETASTATIN A-4 Preparation Products And Raw materials
Raw materials
Isovanillin Copper Quinoline Acetic anhydride Triethylamine 3,4,5-Trimethoxyphenylacetic acid Hydrochloric acid
Preparation Products
COMBRETASTATIN A-4 Suppliers      Global( 75)Suppliers     
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Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969020-39119999isunpharm@qq.com, isunpharm@hotmail.comCHINA 4836 55
Shanghai Boyle Chemical Co., Ltd. Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)86-21-57758967sales@boylechem.comCHINA 5604 55
J & K SCIENTIFIC LTD. ----jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96847 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)sh@meryer.comCHINA 40407 62
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:1893055203786-21-5032810967055399@qq.comCHINA 15983 69
ZHIWE CHEMTECH CO LTD 021-20221225;13917446399；QQ:2381298399 sales@zhiwe.net;zwchem@163.comCHINA 297 61
TCI (Shanghai) Development Co., Ltd. ----info@chemicalbook.comCHINA 22159 81
BeiJing Hwrk Chemicals Limted 4006990298 010-57411839 020-31335234 021-51691807010-87653215 0757-86311057 021-55236763sales@hwrkchemical.comCHINA 12649 55
Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd. +86 (21) 5482-0552086-21-64964478sales@subochem.comCHINA 975 66
Secco work (Beijing) chemical technology co., LTD 010-69755668; 62507480010-697556681139670422@qq.comCHINA 3551 54
 
117048-59-6(COMBRETASTATIN A-4)Related Search:
3-(3-Hydroxy-4-methoxy-phenyl)-2-(3,4,5-trimethoxy-phenyl)-acrylic acid COMBRETASTATIN A1 Combretastatin A4 disodium phosphate BENZENEACETIC ACID, 3-HYDROXY-4-METHOXY-A-[(3,4,5-TRIMETHOXYPHENYL)METHYLENE]-, (AE)- (Z)-3-Ethoxy-6-(3,4,5-Trimethoxystyryl)Benzene-1,2-Diol COMBRETASTATIN A-4 2,3-DIMETHOXY-5-[(Z)-2-(4-METHOXY-3-(2-[2-((1-[(4-METHYLPHENYL)SULFONYL]-1H-INDOL-4-YL)OXY)ETHOXY]ETHOXY)PHENYL)ETHENYL]PHENYL METHYL ETHER Combretastatin A-1 di-O-phosphate tetra-sodium salt
117048-59-6 (Z)-2-Methoxy-5-(3,4,5-Trimethoxystyryl)Phenol (Z)-2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenol,3,4,5-Trimethoxy-3hydroxy-4methoxy-(Z)-stilbene,CS-A4 Combrestatin A4( 2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol ) Inhibitors Combretastatin (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol ,98% 2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol 3-[(Z)-2-(3,4,5-Trimethoxyphenyl)ethenyl]-6-methoxyphenol 5-[(Z)-2-(3,4,5-Trimethoxyphenyl)ethenyl]-2-methoxyphenol Combretastatin A4 (Z)-CombretastatinA4 17048-59-6 combretastatin A-4 (CA-4) 2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol CA-4, Combretastatin A-4 1-(3,4,5-Trimethoxyphenyl)-2-(3′-hydroxy-4′-methoxyphenyl) ethane 3,4,5-trimethoxy-3′-hydroxy-4′-methoxystilbene CA4 Combrestatin A4 (Z)-2-Methoxy-5-[2-(3,4,5-triMethoxyphenyl)ethenyl]phenol, 3,4,5-TriMethoxy-3'-hydroxy-4'-Methoxy-(Z)-stilbene CS-A4 CoMbretastatin A Anti-cancer & immunity (Z)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol
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